Vijaya Sunkhara

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Interferon-a (IFN-a) has been well known to cause both dose-dependent and idiosyncratic toxicities. The dose-dependent side effects, which include flulike symptoms, leukopenia, anemia, and thrombocytopenia, improve upon dose reduction. In contrast, hypothyroidism and autoimmune phenomena improve only after discontinuation of therapy (1, 2). Although several(More)
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