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Functional genetic variants of CTLA-4 and risk of tobacco-related oral carcinoma in high-risk North Indian population.
Single nucleotide polymorphisms (SNPs) of the CTLA-4 gene have been implicated in susceptibility to different cancer in different ethnic populations. We assessed the association of five SNPs… Expand
Operculina turpethum extract inhibits growth and proliferation by inhibiting NF-κB, COX-2 and cyclin D1 and induces apoptosis by up regulating P53 in oral cancer cells.
- R. Arora, Vijaya Bharti, P. Gaur, S. Aggarwal, M. Mittal, S. Das
- Medicine, Biology
- Archives of oral biology
- 1 August 2017
OBJECTIVES Herbal drugs are popularly emerging as complementary and alternative medicines in cancer patients because of their cost effectiveness and minimal side-effects. The extract of Operculina… Expand
COMMIPHORA MUKUL EXTRACT AND GUGGULSTERONE EXHIBIT ANTITUMOUR ACTIVITY THROUGH INHIBITION OF CYCLIN D1, NF-Κß AND INDUCTION OF APOPTOSIS IN ORAL CANCER CELLS
ABSTRACT Comiphora mukul, a promising medicinal plant and its constituent Guggulsterone (GS) is used in Ayurveda since decades. This study was aimed to investigate the anticancer potential of C.… Expand