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  • Estelle Bettelli, Maria Pagany, Howard L Weiner, Christopher Linington, Raymond A Sobel, Vijay K Kuchroo
  • Medicine
  • The Journal of experimental medicine
  • 2003 (First Publication: 5 May 2003)
  • Multiple sclerosis (MS) is considered to be an autoimmune disease of the central nervous system (CNS) that in many patients first presents clinically as optic neuritis. The relationship of opticExpand
  • Kaori Sakuishi, Lionel Apetoh, Jenna M Sullivan, Bruce R. Blazar, Vijay K Kuchroo, Ana C. Anderson
  • Biology, Medicine
  • The Journal of experimental medicine
  • 2010 (First Publication: 27 September 2010)
  • The immune response plays an important role in staving off cancer; however, mechanisms of immunosuppression hinder productive anti-tumor immunity. T cell dysfunction or exhaustion in tumor-bearingExpand
  • Anneli Jäger, Valérie Dardalhon, Raymond A Sobel, Estelle Bettelli, Vijay K Kuchroo
  • Biology, Medicine
  • The Journal of Immunology
  • 2009 (First Publication: 1 December 2009)
  • Experimental autoimmune encephalomyelitis (EAE) is a model of human multiple sclerosis induced by autoreactive Th cells that mediate tissue inflammation and demyelination in the CNS. Initially,Expand