Unsupervised K-means cluster analysis and self-organizing maps (SOM) were employed to cluster patients based on feature values in the large Digitalis Investigation Group (DIG) trial database of digoxin for heart failure treatment. We observed that use of standardized features for input into SOM resulted in clusters for which the pattern of features were… (More)
We studied heart failure mortality and hospitalization of N=7,788 subjects in the Digitalis Intervention Group (DIG) clinical trial. Cases were defined as subjects with New York Heart Association (NYHA) class III–IV symptoms, while controls were defined as subjects with NYHA class I–II symptomatology. Controls were propensity matched with… (More)
Hepcidin does not mediate anemia in chronic heart failure patients, and is suppressed in chronic heart failure. Abstract The Role of Valsartan and Carvedilol in Patients with Chemotherapy Associated Cardiomyopathy Who Are Intolerant to Angiotensin Converting Enzyme Inhibitors.