Vidhyalakshmi Arumugam

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Transforming Growth Factor b (TGFb) is an immunosup-pressive cytokine that inhibits pro-inflammatory functions of T cells, and is a major contributor to abrogating T H 1 and cytotoxic T cell activity against tumors. While canoni-cal signal transduction through effector Smads has been well-defined as a requirement for TGFb-mediated inhibition of T cells,(More)
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