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Somatic mutations in the phosphatidylinositol/AKT/mTOR pathway cause segmental overgrowth disorders. Diagnostic descriptors associated with PIK3CA mutations include fibroadipose overgrowth (FAO), Hemihyperplasia multiple Lipomatosis (HHML), Congenital Lipomatous Overgrowth, Vascular malformations, Epidermal nevi, Scoliosis/skeletal and spinal (CLOVES)(More)
OBJECTIVES The objective of this study was to estimate the risk of recurrent obstetric anal sphincter injury (rOASI) in women who have suffered anal sphincter injury in their previous pregnancy and analyse risk factors for recurrence through a systematic review and meta-analysis. DATA SOURCES A review was performed according to Preferred Reporting Items(More)
Historically, nursing students have shown great difficulty in mastering equipment during clinical practice sessions. A typical example is the Intravenous (IV) pump infusion driver. Traditional training methods have relied upon on-campus practical group training sessions. Recent work in this area has demonstrated that Remote Access Laboratories (RAL) can be(More)
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