Victoria Nahum

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n u s u a l s u s p e c t s • s o c ia l p r o o f • s e lf o r g a n iz a t io n • li b e r a t in g s t r u c t u r e s • p o s it iv e d e v ia n c e • c o m p le x it y • e m e r g e n t o u t c o m e s • in v it a t io n • d is c o v e r y a n d a c t io n • n e t w o r k m a p p in g • n o n li n e a r it y • u n u s u a l s u s p e c t s • s o c ia l(More)
We previously developed orthosteric M1 muscarinic agonists (e.g. AF102B, AF267B and AF292), which act as cognitive enhancers and potential disease modifiers. We now report on a novel compound, AF710B, a highly potent and selective allosteric M1 muscarinic and σ1 receptor agonist. AF710B exhibits an allosteric agonistic profile on the M1 muscarinic receptor;(More)
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