Victoria A. Epstein

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Acute fulminant invasive fungal sinusitis in an immunocompromised host and bacterial rhinosinusitis with intracranial or orbital extension are challenging to manage and constitute true otolaryngic emergencies. In the absence of rapid diagnosis and treatment, these diseases can be fatal. In this article, the complications of bacterial rhinosinusitis are(More)
OBJECTIVE To determine the effects of eosinophilic inflammation on olfactory sensory neuron cell death. STUDY DESIGN Mice were sensitized to intranasal Aspergillus fumigatus extract and subsequently challenged acutely or chronically with the same allergen. The olfactory neuroepithelium was assessed for immunohistochemical evidence of apoptosis and(More)
OBJECTIVE To determine the prevalence of depressive diagnoses and antidepressant use in various subsets of otolaryngology patients. STUDY DESIGN Academic practice EMR database query. SUBJECTS AND METHODS Over 12,000 consecutive otolaryngology patients were analyzed by primary diagnosis and in three groups: Group 1 (tinnitus, vertigo), Group 2(More)
OBJECTIVE Olfaction is impaired in chronic rhinosinusitis (CRS). The study has two aims: (1) to determine whether changes in cation concentration occur in the olfactory mucus of mice with CRS, which may affect chemo-electrical transduction, (2) and to examine whether these alterations are physiologically significant in humans. STUDY DESIGN Animal study in(More)
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