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OBJECTIVE Our aim was to evaluate the clinical course and management of congenital cervical atresia. STUDY DESIGN This retrospective analysis included 7 patients referred to our clinic and a review of the medical literature. RESULTS Including this case series, 58 cases of congenital cervical atresia have been reported in the literature. Forty-eight(More)
We examined the published relationship between uterine fibroids and reproductive outcomes. Submucosal fibroids had the strongest association with lower ongoing pregnancy rates, odds ratio, 0.5; 95% confidence interval, 0.3-0.8, primarily through decreased implantation. Cumulative pregnancy rates appeared slightly lower in patients with intramural fibroids(More)
Studies of human trisomies indicate a remarkable relationship between abnormal meiotic recombination and subsequent nondisjunction at maternal meiosis I or II. Specifically, failure to recombine or recombination events located either too near to or too far from the centromere have been linked to the origin of human trisomies. It should be possible to(More)
OBJECTIVE To assess the impact of individual bacteria isolated from the vagina and tip of the embryo transfer catheter on live-birth rates. DESIGN Prospective clinical study. SETTING Infertility outpatient clinic of a university hospital. PATIENT(S) Ninety-one women undergoing IVF-ET. INTERVENTION(S) Cultures were obtained from the vagina for(More)
BACKGROUND High-density lipoprotein (HDL) is the sole lipoprotein present in follicular fluid (FF). The objectives of this study were to examine HDL lipid composition and associated enzyme activities in FF and serum and to relate these levels to embryo morphology parameters in women undergoing in vitro fertilization (IVF). METHODS Serum and FF were(More)
OBJECTIVE To determine whether success rates were similar in Asian and Caucasian women undergoing infertility treatment. DESIGN Secondary data analysis and multivariate modeling. SETTING Clinics reporting to the national Society for Assisted Reproductive Technology registry and a university-based clinic. PATIENT(S) Caucasian and self-identified Asian(More)
BACKGROUND Obesity has risen among women in the USA, including those seeking infertility treatments. In 2007, height and weight were added to the Society for Assisted Reproductive Technology Clinic Online Reporting System (SART CORS), permitting calculation of BMI (weight/height(2)) for the first time using this national dataset. METHODS The SART CORS was(More)
OBJECTIVE To evaluate ethnic differences in assisted reproductive technology (ART) outcomes in the United States. DESIGN Historical cohort study. SETTING Clinic-based data. PATIENT(S) A total of 139,027 ART cycles from the Society for Assisted Reproductive Technology Clinic Outcome Reporting System online database for 2004-2006, limited to white,(More)
OBJECTIVE The purpose of this study was to investigate the potential efficacy of high-intensity focused ultrasound for the treatment of uterine fibroid tumors in a nude mouse model. STUDY DESIGN A total of 60 female athymic nude mice were inoculated subcutaneously with 3 to 5 x 10(6) ELT-3 cells, a uterine fibroid tumor cell line. Tumor size was monitored(More)
OBJECTIVE To determine whether bed rest after embryo transfer leads to improved pregnancy rates (PR). DESIGN Randomized controlled trial. SETTING University reproductive health clinic. PATIENT(S) Women undergoing IVF. INTERVENTION(S) Patients undergoing 164 cycles of IVF were randomized to 30 minutes of bed rest after embryo transfer or immediate(More)