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- Annie Pardo, Kevin Gibson, +8 authors Naftali Kaminski
- PLoS medicine
- 2005
BACKGROUND
Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal disorder characterized by fibroproliferation and excessive accumulation of extracellular matrix in the lung.
METHODS AND… (More)
- Marco Checa, Victor Ruiz, Martha Montaño, Rafael Velázquez-Cruz, Moisés Selman, Annie Pardo
- Human Genetics
- 2008
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive fibrotic lung disorder of unknown etiology and unclear pathogenesis. Matrix metalloproteinase-1 (MMP-1) is strongly upregulated and… (More)
- Carolina García-de-Alba, Carina Becerril, +5 authors Annie Pardo
- American journal of respiratory and critical care…
- 2010
RATIONALE
Fibrocytes are progenitor cells characterized by the simultaneous expression of mesenchymal, monocyte, and hematopoietic stem cell markers. We previously documented their presence in lungs… (More)
- Carlos Ramos, Martha Montaño, +5 authors Moisés Selman
- American journal of physiology. Lung cellular and…
- 2006
Fibroblast/myofibroblast expansion is critical in the pathogenesis of pulmonary fibrosis. To date, most research has focused on profibrotic mediators, whereas studies on antifibrotic factors are… (More)
- Francisco Olán, Margarita Portela, +4 authors Manuel Martínez-Lavín
- The Journal of rheumatology
- 2004
Vascular endothelial growth factor (VEGF) is a cytokine overexpressed in hypoxic and malignant pathologies. VEGF induces vascular hyperplasia, new bone formation, and edema. These histological… (More)
- Scott J. Moura, Jan Dimon Bendtsen, Victor Ruiz
- Int. J. Control
- 2014
- Carlos Ramos, Jose Cisneros, Georgina González-Ávila, Carina Becerril, Victor Ruiz, Martha Montaño
- Inhalation toxicology
- 2009
Elastolysis, collagenolysis and gelatinolysis are essential in the pathogenesis of tobacco smoke-induced emphysema; however, these activities have been scantily studied in emphysema secondary to… (More)
- Arnoldo Aquino-Gálvez, M. Mercedes Pérez-Rodríguez, +9 authors Moisés Selman
- Human Genetics
- 2009
Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal lung disorder of unknown etiology. IPF is likely the result of complex interrelationships between environmental and host factors,… (More)
- Marco Checa, James S Hagood, +11 authors Moisés Selman
- PloS one
- 2016
Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal disease of unknown etiology. A growing body of evidence indicates that it may result from an aberrant activation of alveolar… (More)
- Annie Pardo, Victor Ruiz, +7 authors Moisés Selman
- American journal of respiratory and critical care…
- 2003
To investigate repair mechanisms in bleomycin-induced pulmonary fibrosis, we used mice deficient in gamma-glutamyl transpeptidase (GGT-/-), a key enzyme in glutathione (GSH) and cysteine metabolism.… (More)