Victor Rosales

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Dengue is the most important mosquito-borne viral infection in humans. Recent evidence suggests that vitamin D influences virus replication. In this work, the effect of vitamin D treatment on dengue virus infection in human hepatic Huh-7 cells and on virus infection and cytokine production in the human monocytic U937 cells was evaluated. Exposure to(More)
Severe dengue (SD) is a life-threatening complication of dengue that includes vascular permeability syndrome (VPS) and respiratory distress. Secondary infections are considered a risk factor for developing SD, presumably through a mechanism called antibody-dependent enhancement (ADE). Despite extensive studies, the molecular bases of how ADE contributes to(More)
BACKGROUND Persistence of respiratory syncytial virus (RSV) has been associated with episodes of chronic obstructive pulmonary disease (COPD); furthermore, co-infection of RSV with non-typeable Haemophilus influenzae (NTHi) is increasingly recognized as a cause of exacerbations of COPD. OBJECTIVE To study whether RSV persistence in a macrophage (Mφ)-like(More)
DNA hypermethylation and histone deacetylation are epigenetic events that contribute to the absence or downregulated expression of different components of the tumor recognition complex. These events affect the processing and presentation of antigenic peptides to CTLs by HLA class-I molecules. In this work evaluated the effect of the DNA hypomethylating(More)
Open Access Meeting abstract Up-regulation of HLA class I antigen expression and antigen-specific CTL response in cervical cancer cells by the demethylating hydralazine and the histone deacetylase inhibitor valproic acid María de Lourdes Mora-García*1, Alfonso Duenas-González2, Jorge Hernández-Montes1, Benny Weiss-Steider1, Edelmiro Santiago-Osorio3,(More)
This paper presents a language for courseware design that tries to overcome usability limitations shown by the Course Modeling Technique (CMT). The proposed language is able to deal with the key aspects of courseware design: objectives, contents, and instructional path. Given that its potential users are non-technical, the representation of the language is(More)
This paper discusses how to decrease and stabilize network latency in a Beowulf system. Having low latency is particularly important to reduce execution time of High Performance Computing applications. Optimization opportunities are identified and analyzed over the different system components that are integrated in compute nodes, including device drivers,(More)
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