Victor Gane

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Anti-Tat vaccination experiments were carried out in mice with a view to inducing systemic in addition to mucosal immunity. For this, three types of immunizing preparations were tested, which consisted of Tat toxoid embedded in either an adjuvant oily structure (IMS), or nanoparticles of chitosan, or microparticles of polylactide-co-glycolide (PLG).(More)
1474-0346/$ see front matter 2012 Elsevier Ltd. A http://dx.doi.org/10.1016/j.aei.2012.04.008 ⇑ Corresponding author. Tel.: +1 650 265 8449. E-mail addresses: vgane@alum.mit.edu (V. Gane) Haymaker). This paper presents a novel methodology called Design Scenarios (DSs) intended for use in conceptual design of buildings. DS enables multidisciplinary design(More)
Quality designs generally emerge from a conceptual design process that generates and communicates large design spaces of objectives, alternatives, impacts, and values. Parametric modeling is a popular means for generating large alternative spaces but it is difficult to use effectively when the other spaces are not well generated. We apply a framework for(More)
This paper presents a novel methodology called Design Scenarios (DS) intended for use in conceptual design of buildings. DS enables multidisciplinary design teams to streamline the requirements definition, alternative generation, analysis, and decisionmaking processes by providing a methodology for building and managing requirements driven design spaces(More)
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