Vicente Palop

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Scarce information about comparative diagnostic and therapeutic patterns in paediatric outpatients of different countries is found in the literature. To describe the similarities and differences observed in diagnosis and therapeutic patterns of paediatric patients of seven locations in different countries. Cross-sectional, prospective, international(More)
OBJECTIVE To analyze the case reports concerning children (14 years or younger) in the Spanish Pharmacovigilance System over a 10-year period (1982-1991). FINDINGS The study of 1419 reports of adverse drug reaction (9.8% of all those received) showed the most commonly involved organs and systems to be the skin, digestive tract, and nervous system (62.8%).(More)
AIMS There are few publications of adverse drug reactions (ADRs) among paediatric patients, though ADR incidence is usually stated to be higher during the first year of life and in male patients. We have carried out a prospective study to assess the extent, pattern and profile risk for ADRs in hospitalized patients between 1 and 24 months of age. METHODS(More)
BACKGROUND Benzodiazepines are extensively used in primary care, but their long-term use is associated with adverse health outcomes and dependence. AIMS To analyse the efficacy of two structured interventions in primary care to enable patients to discontinue long-term benzodiazepine use. METHOD A multicentre three-arm cluster randomised controlled trial(More)
OBJECTIVE To analyze whether for an equal health problem there are gender differences in the drugs used in an adult population attended in the Health Care Centers of the Valencian Community (Spain). METHODS A cross-sectional analytical study was carried out between February-August 1997. The independent variables were: socio-economic parameters, frequency(More)
BACKGROUND Indication-based, in comparison to diagnoses-based, drug utilization studies in children are scarce in the literature. AIM To determine the adequacy of the prescriber's indications for specific drug treatments compared to the current literature in five different European countries; and to show the possibilities of performing indication-based(More)
BACKGROUND Although benzodiazepines are effective, long-term use is not recommended because of potential adverse effects; the risks of tolerance and dependence; and an increased risk of hip fractures, motor vehicle accidents, and memory impairment. The estimated prevalence of long-term benzodiazepine use in the general population is about 2,2 to 2,6%, is(More)
To describe patterns observed in the treatment of acute otitis media (AOM) in several locations of five countries. Cross-sectional, descriptive study. Random sample of 12,264 paediatric outpatients seen by paediatricians or general practitioners (GPs). Data on patient demographics, diagnoses and treatment were collected. Diagnoses were coded by ICD-9 and(More)