Learn More
HYPOTHESIS Amplification of the HER-2/neu oncogene in 25% of breast cancers is associated with a shortened disease-free survival. DESIGN Retrospective analysis of a patient population referred to a tertiary care facility for HER-2/neu testing. The mean follow-up was 56 months. SETTING Large, urban, tertiary care hospital. PATIENTS From 1995 to 1999, a(More)
BACKGROUND Achalasia is a relatively rare disorder with a variety of treatment options. Although laparoscopic Heller myotomy has become the surgical treatment of choice, little data exist on the overall quality of life of patients undergoing this technique versus standard open approaches. METHODS We prospectively evaluated all patients surgically treated(More)
HYPOTHESIS Data from the 36-Item Short-Form Health Survey (SF-36) do not follow a normal distribution and should not be analyzed using parametric techniques. A novel type of analysis, top-box analysis, may add to the interpretation of these data. DESIGN Review of SF-36 data from preoperative and postoperative patients. SETTING Tertiary care hospital and(More)
Bayesian analysis is a method by which the reliability of diagnostic tests can be determined. It produces a probability of a patient having the disease given a positive test result (posterior probability). If more than one study of a given test's diagnostic accuracy is done, then how can we determine which of these studies has produced the most reliable(More)
An underlying assumption of quality of life outcome research is that after some intervention a "steady-state" of quality of life is reached which can be identified as an endpoint, and, hence, the "outcome." However, in some disease processes, no so such steady-state is reached. The hypothesis presented is that a disease process with a waxing and waning(More)
Primary peritoneal cystadenocarcinoma is a rare tumor of similar histogenic origin as primary ovarian carcinoma. We present a case of primary peritoneal serous cystadenocarcinoma mimicking advanced colorectal cancer in a 68 yr-old African American female. Radiology, endoscopy and cytology yielded only inconclusive findings. Immunohistochemical analysis of(More)
  • 1