Viên Nguyen

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This paper is concerned with Brownian system models that arise as heavy traffic approximations for open queueing networks. The focus is on model formulation, and more specifically, on the formulation of Brownian models for networks with complex routing. We survey the current state of knowledge in this dynamic area of research, including important open(More)
Protein carbonylation has been associated with various pathophysiological processes. A representative reactive carbonyl species (RCS), 4-hydroxy-2-nonenal (HNE), has been implicated specifically as a causative factor for the initiation and/or progression of various diseases. To date, however, little is known about the proteins and their modification sites(More)
Potential prodrugs for the TRH-like tripeptide pGlu-Glu-Pro-NH(2) were synthesized either by esterifying the Glu side-chain of the parent peptide in solution with alcohols in the presence of resin-bound dicyclohexylcarbodiimide or by solid-phase peptide chemistry. Affinities of these ester prodrugs to lipid membranes as predictors of the transport across(More)
In heavy traffic analysis of open queueing networks, processes of interest such as queue lengths and workload levels are generally approximated by a multidimensional reflected Brownian motion (RBM). Decomposition approximations, on the other hand, typically analyze stations in the network separately, treating each as a single queue with adjusted(More)
We study several variations of a multiclass closed queueinp network model, all closely related to the open priority network of Lu and Kumar. Foi each of our examples it is shown that, as the population size n —• oo, the long-run utilization rate of each server approaches a limit strictly less than one. Thus no "bottleneck station" emerges in the heavy(More)
The objective of this study was to investigate the effects of osmolarity of culture media on the development of porcine parthenogenetic diploids. Oocyte-cumulus-granulosa cell complexes were collected from ovaries and then in vitro-cultured for 48 h. The mature oocytes were subjected to a single electro-stimulation (El-St; 100 micros, 1500 V/cm), treated(More)
Alcoholics have increased susceptibility to infections including tuberculosis. Chronic alcohol treatment impairs host response to bovine mycobacterium infection from BCG. This study assesses the role of four cytokines (TNFalpha, IFNgamma, IL-4, and IL-10) in this impaired response. Twenty male C57BL/6 mice were pair-fed on the Lieber DiCarli control (LCD)(More)