Learn More
Validation is arguably the bottleneck in the diffusion magnetic resonance imaging (MRI) community. This paper evaluates and compares 20 algorithms for recovering the local intra-voxel fiber structure from diffusion MRI data and is based on the results of the "HARDI reconstruction challenge" organized in the context of the "ISBI 2012" conference. Evaluated(More)
The recent challenge in diffusion imaging is to find acquisition schemes and analysis approaches that can represent non-gaussian diffusion profiles in a clinically feasible measurement time. In this work we investigate the effect of b-value and the number of gradient vector directions on Q-ball imaging and the Diffusion Orientation Transform (DOT) in a(More)
High-angular resolution diffusion imaging (HARDI) is a diffusion weighted MRI technique that overcomes some of the decisive limitations of its predecessor, diffusion tensor imaging (DTI), in the areas of composite nerve fiber structure. Despite its advantages, HARDI raises several issues: complex modeling of the data, nonintuitive and computationally(More)
High angular resolution diffusion imaging (HARDI) is an emerging magnetic resonance imaging (MRI) technique that overcomes some decisive limitations of its predecessor diffusion tensor imaging (DTI). HARDI can resolve locally more than one direction in the diffusion pattern of water molecules and thereby opens up the opportunity to display and track(More)
Abstract-Any sufficiently smooth, positive, real-valued function &#x03C8; : S<sup>2</sup> &#x2192; K+ on a sphere S<sup>2</sup> can be expanded by a Laplace expansion into a sum of spherical harmonics. Given the Laplace expansion coefficients, we provide a CPU and GPU-based algorithm that renders the radial graph of &#x03C8; in a fast and efficient way by(More)
INTRODUCTION-Deep Brain Stimulation (DBS) of the subthalamic nucleus (STN) for Parkinson's Disease alleviates the motor symptoms, but causes cognitive and emotional side effects in half of the cases [1]. We strive to locate the STN motor part more precisely by analyzing the connections of the STN with other brain areas. This study compares DTI and HARDI(More)
High angular resolution diffusion imaging (HARDI) has proven to better characterize complex intra-voxel structures compared to its predecessor diffusion tensor imaging (DTI). However, the benefits from the modest acquisitions and significantly higher signal-to-noise ratios (SNRs) of DTI make it more attractive for use in clinical research. In this work we(More)
The optic radiation (OR) is one of the major components of the visual system and a key structure at risk in white matter diseases such as multiple sclerosis (MS). However, it is challenging to perform track reconstruction of the OR using diffusion MRI due to a sharp change of direction in the Meyer's loop and the presence of kissing and crossing fibers(More)
Brain networks are becoming forefront research in neuroscience. Network-based analysis on the functional and structural connectomes can lead to powerful imaging markers for brain diseases. However, constructing the structural connectome can be based upon different acquisition and reconstruction techniques whose information content and mutual differences has(More)