Learn More
Striatal dopamine receptors were studied in 44 patients with Parkinson disease by the radioligand-binding technique using 3H-spiroperidol. The specific binding of 3H-spiroperidol was either significantly increased or reduced in the caudate nucleus and putamen of parkinsonian patients without levodopa therapy. Scatchard analysis showed that there were(More)
—A multi-channel time-to-digital converter implemented with 0.35µm CMOS technology is described which uses a low frequency crystal as a reference and measures the time intervals with counter and delay line interpolation techniques. The multi-channel measurement architecture provides information on the time intervals between several timing signals. The(More)
Brain enkephalin receptors were studied in post-mortem brain samples of 27 patients with Parkinson's disease and of 26 control subjects without extrapyramidal disorders by the radioligand-binding technique using 3H-leu-enkephalin, 3H-met-enkephalin and 3H-naloxone. The specific binding of both 3H-leu- and 3H-met-enkephalins was significantly increased in(More)
  • 1