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Targeting leukocyte MMPs and transmigration: minocycline as a potential therapy for multiple sclerosis.
- Veronika Brundula, N. B. Rewcastle, L. Metz, C. Bernard, V. W. Yong
- Brain : a journal of neurology
- 1 June 2002
Multiple sclerosis is characterized by the infiltration of leukocytes into the CNS. As matrix metalloproteinases (MMPs) facilitate the passage of leukocytes across matrix barriers, we tested the… Expand