Veronica Ferrer

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The cellular prion protein (PrP(C)) is a membrane-bound glycoprotein especially abundant in the central nervous system (CNS). The scrapie prion protein (PrP(Sc,) also termed prions) is responsible of transmissible spongiform encephalopathies (TSE), a group of neurodegenerative diseases which affect humans and other mammal species, although the presence of(More)
INTRODUCTION The scrapie prion protein (PrPsc) requires the cellular prion protein (PrPc) for its propagation and replication. In this work we studied the expression and localization of the PrPc in the central nervous system (SNC) of the rat, mouse, cat, cow and human, using immunohistochemistry and Western blot techniques to understand more about(More)
Duchenne Muscular Dystrophy (DMD) is caused by a lack of dystrophin expression in patient muscle fibres. Current DMD gene therapy strategies rely on the expression of internally deleted forms of dystrophin, missing important functional domains. Viral gene transfer of full-length dystrophin could restore wild-type functionality, although this approach is(More)
de tener relación con la fisiopatología de la EA. Cellular prion protein in the central nervous system of mammals. Anatomoclinical associations Abstract Introduction: The scrapie prion protein (PrPsc) requieres the cellular prion protein (PrPc) for its propagation and replication. In this work we studied the expression and localization of * Autor para(More)
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