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  • Veronica A. Carroll, Margaret Ashcroft
  • Biology, Medicine
  • Cancer research
  • 2006 (First Published: 15 June 2006)
  • Overexpression of hypoxia-inducible factors (HIF), HIF-1alpha and HIF-2alpha, leads to the up-regulation of genes involved in proliferation, angiogenesis, and glucose metabolism and is associatedContinue Reading
  • Veronica A. Carroll, Leonid L. Nikitenko, Roy Bicknell, Adrian L Harris
  • Biology, Medicine
  • Arteriosclerosis, thrombosis, and vascular…
  • 2005 (First Published: 1 April 2005)
  • OBJECTIVE The thrombolytic therapy drug, Reteplase, is a domain deletion mutant of tissue plasminogen activator (tPA), comprising the kringle 2 and protease (K2P) domains. Some kringle domains ofContinue Reading