Vernon J. Rogers

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BACKGROUND Orexins are neuromediators that help regulate many different physiological processes; however, their role in regulating immune system functioning is unclear. This study sought to investigate the distribution of orexin in hypothalamic orexin-containing neurons during the first 6 hours after an intravenous injection of a lipopolysaccharide. (More)
The influences of different treatments on the expression of the c-fos gene in the spinal cord and brain (hypothalamus) was studied in rats using various types of anesthesia. Synthesis of c-Fos-like proteins occurred only in the spinal cord in conditions of constant 1.5% halothane anesthesia. Use of induction anesthesia with 1.5% halothane allowed detection(More)
OBJECTIVES The purpose of this study was to determine: 1) The spatial pattern of c-fos gene expression in rat hypothalamic neurons after exposure to NMS and 2) The expression of c-fos gene after combined exposure to NMS and EHF irradiation of the rat skin. METHODS The experiments were performed on 28 male adult Sprague-Dawley rats. After rats were(More)
Studies of the pattern of activation of hypothalamic cells in conditions of electrical pain stimulation demonstrated an increase in the proportion of c-Fos-positive cells (to 72.02-98.95%), predominantly affecting cells of size 10-50 microm2. UHF irradiation of the skin activated hypothalamic cells of size 10-70 microm2 in the paraventricular and(More)
A morphometric analysis of hypothalamic cells containing c-Fos-like protein detected by an indirect immunoperoxidase method was carried out to clarify the responses to movement restriction and skin electromagnetic high frequency (EHF) irradiation (7.1mm, 42.2GHz, 20mW output power) simultaneously to three acupuncture projection areas. The morphometry of(More)
C-fos gene expression induced in cells in specifi c hypothalamic structures by noxious mechanical stimulation and it's modifi cation by exposure of the skin to extremely high frequency irradiation Abstract OBJECTIVES : The purpose of this study was to determine: 1. The spatial pattern of c-fos gene expression in rat hypothalamic neurons after exposure to(More)
Orexins are neuromediators that participate in the regulation of feeding behavior, energy metabolism, circadian rhythms and perception of pain. The aim of the present study was to clarify the responses of the hypothalamic orexin-containing neurons to an intraperitoneal injection of cyclophosphamide (CPA), extremely high frequency (EHF)-electromagnetic(More)
BACKGROUND The goal was to assess changes in natural killer (NK) cell activity and the number of c-Fos-positive cells in hypothalamic structures induced by painful electrical stimulation and to use extremely high-frequency (EHF) irradiation of the skin to modulate these processes. MATERIAL/METHODS Experiments were performed on Wistar rats subjected to(More)
C-fos gene expression was studied as a marker of nervous cells activation in the rat spinal cord and brain cells under different conditions (different kinds of narcosis). Using of 1.5% light halothane narcosis allowed the detection of c-Fos-like proteins expression in the spinal cord cells only. Under initial 1.5% halothane narcosis, c-Fos-like proteins(More)