Vernon D Larson

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OBJECTIVE The aim of this study was to identify auditory frequencies at which serial threshold testing would provide the greatest sensitivity for early detection of ototoxicity. The overall objective is to develop a more time-efficient ototoxicity monitoring protocol. DESIGN Threshold data were analyzed from 370 hospitalized patients treated with(More)
Reference threshold sound-pressure levels were established for a new insert earphone, the ER-3A tubephone, and for the TDH-50 earphone. In test-retest comparisons, the tubephone produced estimates of auditory threshold as reliable as the thresholds produced by the supraaural earphone. Reference thresholds were developed for the two earphones from data(More)
Therapeutic drugs such as the aminoglycoside antibiotics (AMG) and the chemotherapy agent cisplatin (CDDP) are known to cause irreversible hearing loss, typically affecting highest frequency hearing first with progression of loss to the lower frequency regions. Conventional (0.25-8 kHz) and high-frequency (9-20 kHz) serial hearing threshold monitoring was(More)
Several audiological tests require knowledge of the sound-pressure spectrum at the eardrum. However, microphone readings are typically made at another, more-accessible position in the auditory canal. Recordings are then "adjusted" to the plane of the eardrum via mathematical models of the ear canal and eardrum. As bandwidths of audiological instruments have(More)
CONTEXT Numerous studies have demonstrated that hearing aids provide significant benefit for a wide range of sensorineural hearing loss, but no carefully controlled, multicenter clinical trials comparing hearing aid efficacy have been conducted. OBJECTIVE To compare the benefits provided to patients with sensorineural hearing loss by 3 commonly used(More)
OBJECTIVE Because the NIDCD/VA Hearing Aid Clinical Trial was conducted across eight clinical sites, rigorous control of the electroacoustic characteristics of the experimental devices was required. DESIGN The parameters monitored included the gain and output of the approximately 720 hearing aids in the trial, measured both in the 2 cm3 coupler and in(More)
The evaluation of hearing aid performance with young, nonverbal children traditionally consists of a comparison between aided and unaided thresholds. Alternative evaluation procedures include those that provide an estimate of the speech spectrum area that is potentially audible to the child with amplification. This study compared the hearing aid performance(More)
Two clinical word discrimination tests, the Northwestern University Auditory Test No. 6 (NU-6) and the Modified Rhyme Test (MRT), were examined for internal consistency and for split-half reliability under varying primary-to-secondary ratios (P:S) in normal hearers. Although the statistical analysis indicated that half-lists could be used reliably for both(More)
OBJECTIVE Although numerous studies have demonstrated that hearing aids provide significant benefit, carefully controlled, multi-center clinical trials have not been conducted. A multi-center clinical trial was conducted to compare the efficacy of three commonly used hearing aid circuits: peak clipping, compression limiting, and wide dynamic range(More)
OBJECTIVE Subjective measures of performance were assessed on three different hearing aid circuits as part of a large clinical trial. These measurements included the Profile of Hearing Aid Performance and a subjective ranking of individual preference. DESIGN A multi-center, double-masked clinical trial of hearing aids was conducted at eight VA Medical(More)