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- Publications
- Influence
A Method for the Acute and Rapid Degradation of Endogenous Proteins
Summary Methods for the targeted disruption of protein function have revolutionized science and greatly expedited the systematic characterization of genes. Two main approaches are currently used to… Expand
d-chiro-Inositol Ribophostin: A Highly Potent Agonist of d-myo-Inositol 1,4,5-Trisphosphate Receptors: Synthesis and Biological Activities
- S. Mills, A. M. Rossi, Vera Konieczny, D. Bakowski, C. Taylor, B. L. Potter
- Chemistry, Medicine
- Journal of medicinal chemistry
- 13 February 2020
Analogues of the Ca2+-releasing intracellular messenger d-myo-inositol 1,4,5-trisphosphate [1, Ins(1,4,5)P3] are important synthetic targets. Replacement of the α-glucopyranosyl motif in the natural… Expand