• Citations Per Year
Learn More
Cytomegalovirus (CMV), a betaherpesvirus, causes significant human morbidity and mortality. It is present in at least 60% of the US population [1], with a prevalence of 90% in high-risk groups, including men who have sex with men [2, 3]. In immunocompetent hosts, CMV infection is usually asymptomatic, but it persists throughout an individual’s lifetime and(More)
Breast cancer is a serious illness affecting approximately one in nine women in the United States. Although an actual cause for breast cancer is unknown, genetic and environmental factors have been associated with its onset. Elevated levels of estrogen and heightened expression of the WNT10B proto-oncogene have been implicated in the development of human(More)
BACKGROUND In this study, we investigated the effect of Didox (DX) on the pathogenicity of and host responses to murine cytomegalovirus (MCMV) infection. METHODS In vitro efficacy of DX against MCMV was determined using plaque reduction assays. For in vivo studies, mice infected with a sublethal dose (10(4) PFU) of MCMV were treated daily with DX (200(More)
  • 1