Ventsislav Rusinov

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Regulation of post-transcriptional gene expression by microRNAs (miRNA) has so far been validated for only a few mRNA targets. Based on the large number of miRNA genes and the possibility that one miRNA might influence gene expression of several targets simultaneously, the quantity of ribo-regulated genes is expected to be much higher. Here, we describe the(More)
In this study we present a method of identifying Arabidopsis miRNA promoter elements using known transcription factor binding motifs. We provide a comparative analysis of the representation of these elements in miRNA promoters, protein-coding gene promoters, and random genomic sequences. We report five transcription factor (TF) binding motifs that show(More)
MicroRNAs (miRNAs) are one of the most abundant groups of regulatory genes in multicellular organisms, playing important roles in many fundamental cellular processes. More than four hundred miRNAs have been identified in humans and the deregulation of miRNA expression has been also shown in many cancers. Despite the postulated involvement of miRNAs in(More)
The stage of dominant discontinuation (ending) was studied on the model of "polarization dominant". The dominant focus was created in rabbits at the site of forepaw projection in the cortex. On reaching the dominant optimum it was disrupted (DC was switched off) after summation (forepaw movement) in response to eye stimulation by an air puff. In the next(More)
Recent research data reveal complex, network-based interactions between mobile elements and regulatory systems of eukaryotic cells. In this article, we focus on regulatory interactions between Alu elements and micro RNAs (miRNAs). Our results show that the majority of the Alu sequences inserted in 3’UTRs of analyzed human genes carry strong potential target(More)
Recent research data reveal complex, network-based interactions between mobile elements and regulatory systems of eukaryotic cells. In this article, we focus on regulatory interactions between Alu elements and micro RNAs (miRNAs). Our results show that the majority of the Alu sequences inserted in 3'UTRs of analyzed human genes carry strong potential target(More)
This Technical Design Report is dedicated to Tom Ypsilantis. Tom conceived the Ring Imaging Cherenkov detectors for particle identification in LHCb and he made an inestimable contribution to the LHCb RICH project. Tom would have wished to see these detectors in operation. He was totally dedicated to the project. He will be missed by the RICH group for his(More)
"Locked-in" state differs from the known states characterized by the motor activity blockade, preservation of conscience of speech contact, despite the fact that connection with outer world during this state is limited only by vertical movements of eyes and eyelids in response to speech signals. Three "locked-in" men were studied at different stages of(More)