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Pharmacokinetics and tissue distribution of etoposide delivered in parenteral emulsion.

• Ram Reddy Patlolla, Venkateswarlu Vobalaboina
• Journal of pharmaceutical sciences
• 2005

Etoposide was incorporated in an injectable parenteral emulsion, in an attempt to alter its pharmacokinetics and improve anticancer activity. Parenteral emulsion of etoposide (EPE), which remained… (More)

Simultaneous Determination of Atorvastatin and Glimepiride by LC-MS / MS in Human Plasma and Its Application to a Pharmacokinetic Study

• Kishore Kumar Hotha, Narasimha Reddy Yarramu, Thriveni Kandibedala, Vijaya Bharathi Dasari, Venkateswarlu Vobalaboina
• 2013

The aim of the proposed research work was to develop and validate a simple, selective, high sensitive and high-throughput assay for the simultaneous estimation of Atorvastatin and Glimepiride in… (More)

Folate-targeted etoposide-encapsulated lipid nanospheres.

• Ram Reddy Patlolla, Venkateswarlu Vobalaboina
• Journal of drug targeting
• 2008

Lipid nanospheres (LN) are simple colloidal drug delivery systems, which are proven to be useful for the systemic delivery of lipophilic anticancer drugs. Our previous work shows that the… (More)

Design and evaluation of polymeric coated minitablets as multiple unit gastroretentive floating drug delivery systems for furosemide.

• Lingam Meka, Bhaskar Reddy Kesavan, +4 authors Madhusudan Rao Yamsani
• Journal of pharmaceutical sciences
• 2009

A gastro retentive floating drug delivery system with multiple-unit minitablets based on gas formation technique was developed for furosemide. The system consists of core units (solid dispersion of… (More)

Antileishmanial activity, pharmacokinetics and tissue distribution studies of mannose-grafted amphotericin B lipid nanospheres.

• Prabhakar reddy Veerareddy, Venkateswarlu Vobalaboina, Nahid Abdelgadir Ali
• Journal of drug targeting
• 2009

Leishmania parasite resides mainly in the liver and the spleen and multiplies. Effective therapy of leishmaniasis could be achieved by delivering antileishmanial drugs to these sites. Present… (More)

Pharmacokinetics and tissue distribution of piperine in animals after i.v. bolus administration.

• Gangadhar Sunkara, Sripal Reddy Mada, Venkateswarlu Vobalaboina
• Die Pharmazie
• 2001

A reverse phase HPLC method to determine piperine, a pungent constituent of black pepper, in rabbit serum and various tissues of the rat was developed. A pharmacokinetic study was performed in… (More)

Bioequivalence of two lansoprazole delayed release capsules 30 mg in healthy male volunteers under fasting, fed and fasting-applesauce conditions: a partial replicate crossover study design to…

• Sammaiah Thota, S. M. Khan, Sudhakar Koundinya Tippabhotla, Ramesh Babu Battula, Chaitanya Gadiko, Venkateswarlu Vobalaboina
• Drug research
• 2013

An open-label, 2-treatment, 3-sequence, 3-period, single-dose, partial replicate crossover studies under fasting (n=48), fed (n=60) and fasting-applesauce (n=48) (sprinkled on one table spoonful of… (More)

Bioequivalence of fixed dose combination of atorvastatin 10 mg and aspirin 150 mg capsules: a randomized, open-label, single-dose, two-way crossover study in healthy human subjects.

• Sudhakar Koundinya Tippabhotla, M R Betha, +7 authors Venkateswarlu Vobalaboina
• Drug research
• 2013

The present study evaluated the bioavailability and bioequivalence of fixed dose combination test formulation (atorvastatin 10 mg and aspirin 150 mg capsule) against marketed reference formulations… (More)

Quaternary salts of 4,3' and 4,4' bis-pyridinium monooximes: synthesis and biological activity.

• Srinivas Rao Chennamaneni, Venkateswarlu Vobalaboina, Achaiah Garlapati
• Bioorganic & medicinal chemistry letters
• 2005

Six unsymmetrical bis-quaternary monooximes viz. dibromides of 1-(4-hydroxyiminomethyl pyridinium)-3-(3/4-carbamoyl pyridinium)propane, 1-(4-hydroxyiminomethyl pyridinium)-4-(3/4-carbamoyl… (More)

Lipid-based formulations of amphotericin B.

• Prabhakar reddy Veerareddy, Venkateswarlu Vobalaboina
• Drugs of today
• 2004

Amphotericin B remains the drug of choice for the treatment of invasive fungal infections and visceral leishmaniasis. However, both the dose-dependent nephrotoxicity and the low response rates… (More)

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