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Pharmacokinetics and tissue distribution of etoposide delivered in parenteral emulsion.
Etoposide was incorporated in an injectable parenteral emulsion, in an attempt to alter its pharmacokinetics and improve anticancer activity. Parenteral emulsion of etoposide (EPE), which remainedExpand
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Design and evaluation of polymeric coated minitablets as multiple unit gastroretentive floating drug delivery systems for furosemide.
A gastro retentive floating drug delivery system with multiple-unit minitablets based on gas formation technique was developed for furosemide. The system consists of core units (solid dispersion ofExpand
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Folate-targeted etoposide-encapsulated lipid nanospheres.
Lipid nanospheres (LN) are simple colloidal drug delivery systems, which are proven to be useful for the systemic delivery of lipophilic anticancer drugs. Our previous work shows that theExpand
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Pharmacokinetics and tissue distribution of piperine lipid nanospheres.
The purpose of this study was to estimate the pharmacokinetic parameters and tissue distribution of positively charged stearylamine (LN-P-SA) and pegylated lipid nanospheres (LN-P-PEG) of piperine inExpand
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Folate-targeted etoposide-encapsulated lipid nanospheres
Lipid nanospheres (LN) are simple colloidal drug delivery systems, which are proven to be useful for the systemic delivery of lipophilic anticancer drugs. Our previous work shows that theExpand
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The Liquisolid technique: an overview
A novel "Powder Solution Technology" involves absorption and adsorption efficiency which makes use of liquid medications, drug suspensions admixed with suitable carriers, coating materials andExpand
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Lipid-based formulations of amphotericin B.
Amphotericin B remains the drug of choice for the treatment of invasive fungal infections and visceral leishmaniasis. However, both the dose-dependent nephrotoxicity and the low response ratesExpand
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Formulation and evaluation of oil-in-water emulsions of piperine in visceral leishmaniasis.
Present studies are aimed to find out the utility of oil-in-water emulsions also known as lipid nanospheres (LN) or fat emulsions for delivering piperine for the treatment of visceral leishmaniasis.Expand
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Antileishmanial activity, pharmacokinetics and tissue distribution studies of mannose-grafted amphotericin B lipid nanospheres
Leishmania parasite resides mainly in the liver and the spleen and multiplies. Effective therapy of leishmaniasis could be achieved by delivering antileishmanial drugs to these sites. PresentExpand
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SEPARATION OF DITERPENOID ALKALOIDS BY HIGH PERFORMANCE CENTRIFUGAL PARTITION CHROMATOGRAPHY
Complex diterpenoid alkaloids of close Rf values have been separated by High Performance Centrifugal Partition Chromatography (HPCPC). Model LLB-M (Series 1000) by Sanki Laboratories Inc. was usedExpand
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