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Cellular chemosensitivity assays: an overview.

• Venil N. Sumantran
• Methods in molecular biology
• 2011

Data on cell viability have long been obtained from in vitro cytotoxicity assays. Today, there is a focus on markers of cell death, and the MTT cell survival assay is widely used for measuring… (More)

Identification of natural compounds which inhibit biofilm formation in clinical isolates of Klebsiella pneumoniae.

• H. Magesh, Arun Kumar, +4 authors Rama Vaidyanathan
• Indian journal of experimental biology
• 2013

Klebsiella pneumoniae, an important opportunistic pathogen, exists as a biofilm in persistent infections and in-dwelling medical devices. With the objective of identifying natural compounds… (More)

Cancer, Inflammation, and Insights from Ayurveda

• Venil N. Sumantran, Girish Tillu
• Evidence-based complementary and alternative…
• 2012

A recent, exciting discovery relates to the concept of "shared pathology" between cancer and metabolic syndrome. One major pathway common to cancer and metabolic syndrome is chronic inflammation,… (More)

Chondroprotective Potential of Fruit Extracts of Phyllanthus emblica in Osteoarthritis

• Venil N. Sumantran, Asavari A. Kulkarni, +4 authors Ulhas V. Wagh
• Evidence-based complementary and alternative…
• 2008

There is a need for effective nutraceuticals for osteoarthritis care. The fruit of Phyllanthus emblica is used as a powerful rejuvenator in Ayurvedic medicine. This study measured the… (More)

Ayurvedic medicine offers a good alternative to glucosamine and celecoxib in the treatment of symptomatic knee osteoarthritis: a randomized, double-blind, controlled equivalence drug trial.

• Arvind Chopra, Manjit Saluja, +9 authors Bhushan Patwardhan
• Rheumatology
• 2013

OBJECTIVE To demonstrate clinical equivalence between two standardized Ayurveda (India) formulations (SGCG and SGC), glucosamine and celecoxib (NSAID). METHODS Ayurvedic formulations (extracts of… (More)

Hyaluronidase and collagenase inhibitory activities of the herbal formulation Triphala guggulu

• Venil N. Sumantran, Asavari A. Kulkarni, +6 authors Ulhas V. Wagh
• Journal of Biosciences
• 2007

Myrrh (guggulu) oleoresin from the Commiphora mukul tree is an important component of antiarthritic drugs in Ayurvedic medicine. Clinical data suggest that elevated levels of hyaluronidase and… (More)

The relationship between chondroprotective and antiinflammatory effects of Withania somnifera root and glucosamine sulphate on human osteoarthritic cartilage in vitro.

• Venil N. Sumantran, Rucha Chandwaskar, +4 authors Ulhas V. Wagh
• Phytotherapy research : PTR
• 2008

Using a validated explant model of in vitro cartilage damage, the effects of aqueous extracts of Withania somnifera (Ashwagandha) root and glucosamine sulphate (GlcS) were tested on the levels of… (More)

Chondroprotective potential of root extracts of Withania somnifera in osteoarthritis

• Venil N. Sumantran, Asavari A. Kulkarni, +6 authors Ulhas V. Wagh
• Journal of Biosciences
• 2007

This is the first report describing two novel chondroprotective activities of aqueous extracts of Withania somnifera root powder. First, these extracts had a statistically significant, short-term… (More)

Experimental approaches for studying uptake and action of herbal medicines.

• Venil N. Sumantran
• Phytotherapy research : PTR
• 2007

In order to gain wider credibility, herbal medicines must go through the rigorous scientific scrutiny to which synthetic drugs are subjected, and this includes investigating their absorption,… (More)

Microarray Analysis of Differentially-Expressed Genes Encoding CYP450 and Phase II Drug Metabolizing Enzymes in Psoriasis and Melanoma.

• Venil N. Sumantran, Pratik Mishra, Rakesh Bera, Natarajan Sudhakar
• Pharmaceutics
• 2016

Cytochrome P450 drug metabolizing enzymes are implicated in personalized medicine for two main reasons. First, inter-individual variability in CYP3A4 expression is a confounding factor during cancer… (More)

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