Venera Mihaela Iliescu

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Growth and differentiation of B cells is thought to be regulated by soluble factors derived from T cells. However, human T cell lines and hybridomas have proved to be notoriously unreliable and unstable sources of such factors. We report here that three stable human bladder carcinoma cell lines T24, RT4 and 5637 produce, in a constitutive fashion, factors(More)
Studies on patients for up to one year following allogeneic, HLA-matched bone marrow transplants have shown no increased incidence of salivary Epstein-Barr (EB) virus secretion and no significant rise in EB-virus-specific antibody titers. EB-virus-specific cytotoxic T cells could be detected in the peripheral blood of all patients by six months(More)
A panel of conventional and monoclonal antibodies was used to examine the immunohistological characteristics of malignant epithelial cells and infiltrating lymphocytes in frozen sections of nasopharyngeal carcinoma (NPC) biopsies from 10 Tunisian patients. Three main categories of cells were identified. (1) Tumour cells which were positive for Epstein-Barr(More)
We have investigated the regression phenomenon which occurs when EBV-infected peripheral blood mononuclear cells from seropositive individuals are cultured for one month at high cell concentration and have confirmed that regression is mediated by E+ lymphocytes. When helper/inducer (Leu 3a+) and suppressor/cytotoxic (Leu 2a+) cells are separated by(More)
Human antimalignin antibody (AMA) appears to have clinical significance because in actuarial studies its concentration relates quantitatively to survival (Bogoch et al. Protides Biol Fluids 1984; 31:739-747). Therefore isolation, characterization, and production in vitro of AMA were undertaken. Serum AMA concentrations are elevated in cancer, regardless of(More)
Microsurgical techniques increased the operability of patients with critical limb ischemia to more than 95%. However, the percentage of ischemic limb salvage remains limited, especially in diabetic patients with associated tissue gangrene and neuropathy. The study presents a 67 years old female patient with type II diabetes mellitus and critical limb(More)
For segmental cervical esophageal reconstruction, the free transfer of jejunal flap tends to become a standard procedure. Graft harvesting by laparotomy presumes increased morbidity at donor area level. There was described by now in the literature laparoscopic techniques for harvesting of jejunal graft, which have reduced the complications following(More)
A case of erythrodermia Sézary, in which lymphocyte stimulation tests and quantitation of T and B lymphocytes were performed, is reported. The patient developed during 10 years of evolution an immunological deficiency with low IgA, IgG and IgM values. Passive hemagglutination techniques showed an antibody titer of 1:8000 against human serum albumin.