Veit M Stoecklein

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The blood-brain barrier (BBB), which prevents the entry into the central nervous system (CNS) of most water-soluble molecules over 500 Da, is often disrupted after trauma. Post-traumatic BBB disruption may have important implications for prognosis and therapy. Assessment of BBB status is not routine in clinical practice because available techniques are(More)
BACKGROUND The on-field diagnosis of sports-related concussion (SRC) is complicated by the lack of an accurate and objective marker of brain injury. PURPOSE To compare subject-specific changes in the astroglial protein, S100B, before and after SRC among collegiate and semi-professional contact sport athletes, and compare these changes to differences in(More)
BACKGROUND Post-traumatic dysfunction of the immune system is a major source of morbidity and mortality in patients with multiple trauma. The underlying intracellular mechanisms are still incompletely understood. Previous mRNA expression studies in monocytes suggested an involvement of the MAP kinases p38 and JNK and of the transcription factor c-Jun.(More)
BACKGROUND Seven years after implementing a new curriculum an evaluation was performed to explore possibilities for improvements. PURPOSES To analyze students' study habits in relation to exam frequency and to evaluate effectiveness of instruction. METHODS Time spent on self study (TSS) and the quantity of instruction (QI) was assessed during the(More)
UNLABELLED Meningiomas are known to express somatostatin receptor 2 (SSTR2). PET using the SSTR2 analog (68)Ga-DOTATATE has recently been introduced for imaging of meningiomas. However, a systematic correlation between (68)Ga-DOTATATE uptake, SSTR2 expression, and histology (including tumor-free scar tissue) is still lacking. For elucidation, we conducted(More)
BACKGROUND The use of intraoperative neurophysiological monitoring (IONM) in neurosurgery has improved patient safety and outcomes. However, a pitfall in the use of IONM remains unsolved. Currently, there is no feasible way for surgeons to interpret IONM waves themselves during operations. Instead, they have to rely on verbal feedback from a(More)
BACKGROUND The prognosis of patients with progressive meningioma after failure of surgery and radiotherapy is poor. METHODS We retrospectively evaluated the safety and efficacy of somatostatin-receptor (SSTR)-targeted radionuclide therapy ((177)Lu-DOTATATE [n = 16], (90)Y-DOTATOC [n = 3], or both [n = 1]) in patients with progressive, treatment-refractory(More)
OBJECTIVE In symptomatic unruptured intracranial aneurysms (UIA), data on long-term functional outcome are sparse in the literature, even in the light of modern interdisciplinary treatment decisions. We therefore analysed our in-house database for prognostic factors and long-term outcome of neurological symptoms after microsurgical/endovascular treatment.(More)
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