Veerle Berckmoes

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Pharmacologically induced stereotypies (PHIS) following dopamine agonists and, more recently, the non-competitive NMDA antagonist dizocilpine (MK-801), are used to study human psychopathology and for screening potential neuroleptic drugs. On the other hand, bank voles (Clethrionomys glareolus) spontaneously develop stereotyped jumping in barren cages,(More)
Fragile X syndrome (FXS), the most common inherited intellectual disability syndrome, is caused by expansion and hypermethylation of the CGG repeat in the 5' UTR of the FMR1 gene. This expanded repeat, also known as the rare fragile site FRAXA, causes X chromosome fragility in cultured cells from patients but only when induced by perturbing pyrimidine(More)
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