Vasily A. Demidov

Learn More
The primary objective of the current study was to estimate the hair toxic metal content in adults in relation to body mass index. A total of 1,229 persons including 719 women and 510 men were examined. All subjects were divided into two age groups: 1 and 2 periods of adulthood. All men and women were also subdivided into groups in relation to their values(More)
During 2003-2006 totally 1470 women 46-60 y.o., living mainly in Moscow city and Moscow region, were observed. There were three groups of women: obese, diabetic and practically healthy. The anthropometric and clinical data were compared with elemental status, estimated by atomic emission and mass spectroscopy with inductively coupled plasma (ICP-AES/ICP-MS)(More)
BACKGROUND Age-related differences in the trace element content of hair have been reported. However, some discrepancies in the data exist. AIM The primary objective of this study was to estimate the change in hair trace elements content in relation to age. SUBJECTS AND METHODS Six hundred and eighteen women and 438 men aged from 10-59 years took part in(More)
A total of 5908 occupationally non-exposed adults (4384 women and 1524 men) living in Moscow and Moscow region were involved in the current investigation. Hair Al, As, Be, Bi, Cd, Hg, Li, Ni, Pb, Sn, and Sr content was estimated by inductively-coupled plasma mass spectrometry using NexION 300D. Men are characterized by significantly higher hair Al, As, Cd,(More)
Appropriate reference values of hair trace element content are required for correct interpretation of biomonitoring data. The primary objective of the current study was to estimate the reference values of selected essential trace elements in hair of adult Russian population. Involved in current investigation were 7256 occupationally non-exposed adults aged(More)
The primary objective of the research is to estimate the dependence between hair mercury content, hair selenium, mercury-to-selenium ratio, serum lipid spectrum, and gamma-glutamyl transferase (GGT) activity in 63 adults (40 men and 23 women). Serum triglyceride (TG) concentration in the high-mercury group significantly exceeded the values obtained for low-(More)
Glutamate-mediated excitotoxicity involving N-methyl-d-aspartate (NMDA) receptors has been recognized as a final common outcome in pathological conditions involving death of retinal ganglion cells (RGCs). Overstimulation of NMDA receptors results in influx of calcium (Ca) and sodium (Na) ions and efflux of potassium (K). NMDA receptors are blocked by(More)
In acute experiments on cats using the method of extracorporeal blood volumometry, the capillary filtration coefficient (CFC) in the skeletal muscle did not correlate with induced changes of arterial pressure (65-280 mm Hg), venous pressure (0-30 mm Hg) and the induced changes of the blood inflow (75-150%). A negative functional relationship was found(More)