Varvara A. Orekhova

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The risk of cardiovascular disease and atherosclerosis progression is significantly increased after menopause, probably due to the decrease of estrogen levels. The use of hormone replacement therapy (HRT) for prevention of cardiovascular disease in older postmenopausal failed to meet expectations. Phytoestrogens may induce some improvements in climacteric(More)
The paper discusses the main approaches to slowing the progression and epy regression of atherosclerosis. Lipid and non-lipid treatment of atherosclerosis described. The results of clinical studies of the effect of antiatherosclerotic agents are analyzed. The main indicator is the thickness of the intima-media complex of the carotid arteries as measured by(More)
A cross-sectional study of intima-medial thickness (IMT) of the carotid arteries in men and women in different age groups was performed as well as a prospective study of the dynamics of carotid IMT changes. It was shown that at the ages 40-70 years IMT is higher in men then in women, but at age after 70 such difference disappears due to acceleration of(More)
The present study evaluated the risks and benefits of phytoestrogen treatment in healthy perimenopausal women in relation to the dynamics of climacteric syndrome and progression of atherosclerosis. Study participants were treated with placebo or phytoestrogen-rich natural preparation Karinat based on grape (Vitis vinifera) seeds, green tea (Camellia(More)
A distribution of the gene frequencies and blood groups of the ABO, Rh, NM and P system in the poles and the byelorussians inthe Grodno region is investigated. The following frequencies of genes in the byelorussians were revealed: r(O)--0,6210; P(A)--0,2451; Q(B)--0,1339; D--0,6093; D-9,3907; M-0,6063; N-0,3937; P(+)-0,4971; P(--)--0,5029; and in poles:(More)
Cultured cell models have been developed to study the cholesterol efflux from the arterial wall as an integral indicator of reverse cholesterol transport. The models and the results of in vivo and ex vivo experiments can be used to propose new antiatherosclerotic drugs and elucidate their mood of action.
A distribution of the gene frequencies and blood groups of the ABO, Rh, NM and P system in the poles and the byelorussians in the Grodno region is investigated. The following frequencies of genes in the byelorussians were revealed: r(0)-0,6210; p(A)-0.2451; q(B)-0,1339; D-0,6093; d-0,3907; M-06063; N-0,3937; P(+)-0,4971; P(-)-0,5029; and in the poles:(More)
A distribution of the gene frequencies and blood groups of the ABO, Rh, NM and P system in the poles and the byelorussians in the Grodno region is investigated. The following frequencies of genes in the byelorussians were revealed: r(0)-0,6210; p(A)--0.2451; q(B)--0,1339; D--0,6093; d--0,3907; M--0,6063; N--0,3937; P(+)-- 0,4971; P(--)--0,5029; and in the(More)
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