Varun Ramamohan

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OBJECTIVE Previous US-based economic models of noninvasive tests for diagnosis of Helicobacter pylori infection did not consider patient adherence or downstream costs of continuing infection. This analysis evaluated the long-term cost-effectiveness of the urea breath test (UBT), fecal antigen test (FAT), and serology for diagnosis of H. pylori infection(More)
BACKGROUND The treatment failure rate for Helicobacter pylori eradication therapy is ~20% due to poor patient compliance and increased antibiotic resistance. This analysis assessed the cost-effectiveness of universal post-treatment testing to confirm eradication of H. pylori infection in adults. METHODS Decision-analytic models evaluated the(More)
Clinical laboratory measurements are vital to the medical decision-making process, and specifically, measurement of rheumatoid factor antibodies is part of the disease criteria for various autoimmune conditions. Uncertainty estimates describe the quality of the measurement process, and uncertainty in calibration of the instrument used in the measurement can(More)
Results of clinical laboratory tests inform every stage of the medical decision-making process, and measurement of enzymes such as alanine aminotransferase provide vital information regarding the function of organ systems such as the liver and gastrointestinal tract. Estimates of measurement uncertainty quantify the quality of the measurement process, and(More)
Clinical laboratory measurement processes inform every stage of the medical decision-making process, and measurement of the activity levels of enzymes such as alkaline phosphatase, alanine aminotransferase, etc. provide vital information regarding various body functions such as the liver and gastrointestinal tract. The uncertainty associated with the result(More)
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