Varun Chalivendra

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To identify potential multiple sclerosis (MS)-specific biomarkers, we used a proteomic approach to screen cerebrospinal fluid (CSF) from 40 MS patients and 13 controls. We identified seven proteins (Beta-2-microglobulin, Bri2-23, Fetuin-A, Kallikrein-6, Plasminogen, Ribonuclease-1, and Transferrin) that had significantly altered levels in MS compared to(More)
To investigate the molecular basis underlying aggressive behavior in oral squamous cell carcinoma (OSCC), our laboratory developed a carcinogen-induced mouse oral cancer (MOC) cell line model that encompasses the growth and metastasis spectrum of its human counterpart. We performed next-generation sequencing (NGS) and gene expression microarray profiles to(More)
Massively parallel finite element simulations of dynamic fracture and fragmentation of brittle solids are presented. Fracture is introduced by the adaptive insertion of cohesive elements. The model is validated against specially designed experiments in a collaborative effort between the experimental and the computational groups. Mesh sensitivity issues are(More)
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