Varinder Athwal

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Autophagy and the unfolded protein response (UPR) both promote activation of hepatic stellate cells (HSC), however the link between the two stimuli remains unclear. Here we have explored the role of X-box binding protein 1 (XBP1), one of three UPR effector pathways and sought to establish the interdependence between autophagy and the UPR during HSC(More)
BACKGROUND To ensure patient safety, rigorous quality assurance (QA) measures for colonoscopy were introduced for the Bowel Cancer Screening Programme (BCSP) in England. The impact of these high QA measures on patient experience and satisfaction is unknown. AIMS To determine the impact of this high-level QA of colonoscopy on patient satisfaction. (More)
Delayed gastric emptying (gastroparesis) is associated with significant morbidity and, occasionally, mortality; clinicians therefore need a high index of suspicion to avoid missing the diagnosis. This review discusses the aetiology, diagnostic criteria and investigations pertinent to gastroparesis, and also critically reviews the evidence for nutritional(More)
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