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- Gopal Murugaiyan, Vanessa Beynon, Akanksha Mittal, Nicole Joller, Howard L. Weiner
- Journal of immunology
- 2011
IFN-γ-producing Th1 and IL-17-producing Th17 cells are the key participants in various autoimmune diseases, including multiple sclerosis and its animal model, experimental autoimmune… (More)
- Jürgen Glas, H Török, +12 authors Elisabeth H. Weiss
- International immunology
- 2007
HLA-G is a non-classical MHC class Ib molecule predominantly expressed in cytotrophoblasts and under pathological conditions also in chronically inflamed and in malignant tissues. Recently an… (More)
- Vanessa Beynon, Francisco J. Quintana, Howard L. Weiner
- PloS one
- 2012
Inflammasomes are multi-protein complexes that control the production of pro-inflammatory cytokines such as IL-1β. Inflammasomes play an important role in the control of immunity to tumors and… (More)
- Gopal Murugaiyan, Vanessa Beynon, Andre Pires Da Cunha, Nicole Joller, Howard L. Weiner
- Journal of immunology
- 2012
IL-9-producing Th9 cells have been associated with autoimmune diseases, such as experimental autoimmune encephalitis. However, the factors that negatively regulate Th9 cells during autoimmune… (More)
- Vanessa Beynon, Sebastian Cotofana, +9 authors H Török
- Inflammatory bowel diseases
- 2008
BACKGROUND
The functional link between mutations in NOD2 and Crohn's disease (CD) has not been entirely elucidated. The 1007fs mutation results in loss of NF-kappaB activation in response to muramyl… (More)
- Akanksha Mittal, Gopal Murugaiyan, Vanessa Beynon, Dan Hu, Howard L. Weiner
- Immunology and cell biology
- 2012
Interleukin (IL)-27 exerts an anti-inflammatory effect on human and mice CD4(+) T cells by inducing IL-10-producing T regulatory 1 cells through induction of IL-21. However, the role of IL-27 and how… (More)
- Maria A Mazzola, Radhika Raheja, +7 authors R. Gandhi
- Multiple sclerosis
- 2017
BACKGROUND
Dimethyl fumarate (DMF) and its active metabolite monomethyl fumarate (MMF) effectively lead to reduction in disease relapses and active magnetic resonance imaging (MRI) lesions. DMF and… (More)
- Radhika Raheja, Keren Regev, +12 authors R. Gandhi
- Muscle & nerve
- 2018
INTRODUCTION
Amyotrophic lateral sclerosis (ALS) is a debilitating neurologic disorder with poor survival rates and no clear biomarkers for disease diagnosis and prognosis.
METHODS
We compared… (More)