Van Vinh Nguyen

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attended by participants from academia and industry, and focused on recent experience from several randomized controlled clinical trials of candidate dengue therapeutic agents [1,2,3]. The aim of this article is to provide an informed set of recommendations for the design and conduct of early-phase clinical trials where safety and antiviral efficacy are the(More)
BACKGROUND Streptococcus suis infection, an emerging zoonosis, is an increasing public health problem across South East Asia and the most common cause of acute bacterial meningitis in adults in Vietnam. Little is known of the risk factors underlying the disease. METHODS AND FINDINGS A case-control study with appropriate hospital and matched community(More)
The PAD Review publications have been made possible by funding from Danish Interna-The designation of geographical entities in this book, and the presentation of the material , do not imply the expression of any opinion on the part of ICEM or other participating organisations concerning the legal status of any country, territory, or area, or of its(More)
Structural design and optimization in engineering address increasingly non-standard optimization problems (NSP). These problems are characterized by complex topology conditions of the optimization space (w.r.t. nonlinearity, multimodality, discontinuity etc.). By that, NSP can only be solved by means of computer simulations. Hereby, the corresponding(More)
• Total recordable cases, rate should be 3.4. • Cases with days away from work, rate should be 1.0. Acknowledgments This document would not have been possible without the cooperation of private industries and governmental agencies in Illinois. The Illinois Department of Public Health wishes to thank them for aiding in gathering data for the Survey of(More)
In this paper we introduce a new method using the zero-norm l<sub>0</sub> for the combined feature selection-supervised classification problem. Discontinuity at the origin for l<sub>0</sub> makes the solution of the corresponding optimization problem difficult. To overcome this drawback we use a robust DC (difference of convex functions) programming(More)
The goal of this research is to develop stable formulations for live attenuated influenza vaccines (LAIV) by employing the drying methods freeze drying, spray drying, and foam drying. Formulated live attenuated Type-A H1N1 and B-strain influenza vaccines with a variety of excipient combinations were dried using one of the three drying methods. Process and(More)