Valiya Parambath Vandana

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OBJECTIVES Reports of audiological manifestations in specific subgroups of mitochondrial disorders are limited. This study aims to describe the audiological findings in patients with MELAS syndrome and m.3243A>G mutation. PATIENTS & METHODS Audiological evaluation was carried out in eight patients with confirmed MELAS syndrome and m.3243A>G mutation. The(More)
BACKGROUND Most of the studies have looked into the effect of typical antipsychotics on speech secondary to tardive dyskinesia. AIMS This study was aimed to explore the factors predicting the effect of atypical antipsychotic medications on the production of speech. MATERIALS AND METHODS One hundred and forty patients on stable regimen of three or more(More)
Speech subsystems are susceptible to the effects of several factors including medications. The atypical antipsychotics can also adversely affect the speech because of its action on serotonin and dopamine neurotransmitters. The present study aims to analyze the speech characteristics associated with atypical antipsychotic risperidone. Speech of 92 patients(More)
Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is a rare mitochondrial disease. The available studies on MELAS syndrome are limited to evaluation of radiological, audiological, genetic, and neurological findings. Among the various neurological manifestations, speech-language and swallowing manifestations(More)
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