Valery V. Kalashnikov

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White rats were immunized against fragment of diazepam-binding inhibitor octadecaneuropeptide (ODN) with conjugate ODN bovine serum albumin. This rats have reduced reactions of fear and anxiety in stress model of "open field" and in conflict Vogel test; their pain sensitivity ("tail flick" test) was lowered. The number and intensity of generalized seizure(More)
Human serum pregnancy-specific beta1-globulin (beta1-GP) was localized in paraffin sections of placenta and chorioepithelioma of the uterus by indirect immunofluorescence. The structures containing beta1-GP but not human serum albumin were regarded as specifically associated with beta1-GP metabolism. Beta1-GP was found in trophoblastic cells of chorion and(More)
Peptide epitopes for tumor-reactive cytotoxic T-lymphocytes (CTL) have been identified on human cancers and are being used in tumor vaccine trials. However, the pharmacokinetics and pharmacodynamics of such peptides have been inadequately studied. It is predicted that immunogenic tumor peptides would have short half-lives in vivo. The goal of the present(More)
The first sandwich-type complexes have been prepared for tetrabenzotriazaporphyrin ligands. The compounds reveal intrinsic UV-Vis/NIR absorption as well as peculiar electrochromic behavior. The heteroleptic (tetrabenzotriazaporphyrinato)(phthalocyaninato) lutetium derivative shows intermediate spectral and electrochemical properties with respect to(More)
A new embryonic antigen was found in ovarian tumors by methods of immunodifusion analysis. This antigen consists of two components with different electrophoretic mobilities: The slow peak migrates in the αo-globulin zone, the fast peak in the prealbumin zone. It is immunologically different from α-fetoprotein and from the carcinoembryonic antigen of the(More)
The presence of embryonic prealbumin (EPA) has been confirmed in fetal fibroblasts, chondrocytes, and distal tubular epithelial cells by an indirect immunoperoxidase technique. EPA has often been found also in the stromal cells of benign and malignant mesodermal tumours, but not in the epithelial cells of benign and malignant epithelial tumours. That EPA is(More)
A new interspecific animal thymus antigen (AgT-2) was identified. It was shown that AgT-2 is a microglobulin with a molecular mass about 12 kDa, electrophoretic mobility of alpha 1-globulins and isoelectric point of 4.6. Heating of the protein to 80 degrees C for 30 min did not lead to the loss of its immunochemical activity. AgT-2 was identified in(More)