Valerie J. Page

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BACKGROUND Delirium is frequently diagnosed in critically ill patients and is associated with poor clinical outcomes. Haloperidol is the most commonly used drug for delirium despite little evidence of its effectiveness. The aim of this study was to establish whether early treatment with haloperidol would decrease the time that survivors of critical illness(More)
RATIONALE Delirium is common in intensive care unit (ICU) patients and is a predictor of worse outcomes and neuroinflammation is a possible mechanism. The antiinflammatory actions of statins may reduce delirium. OBJECTIVES To determine whether critically ill patients receiving statin therapy had a reduced risk of delirium than those not on statins. (More)
BACKGROUND Delirium is an acute organ dysfunction common amongst patients treated in intensive care units. The associated morbidity and mortality are known to be substantial. Previous surveys have described which screening tools are used to diagnose delirium and which medications are used to treat delirium, but these data are not available for the United(More)
AIMS Self-rated health is a widely used measure of general health assessing risk factors and poor health outcomes in health surveys and clinical settings. The characteristics of self-rated health may be different in populations with specific chronic conditions, such as populations with diabetes. This study investigates the characteristics of self-rated(More)
INTRODUCTION Delirium in the intensive care unit (ICU) is associated with increased morbidity and mortality. Using an assessment tool has been shown to improve the ability of clinicians in the ICU to detect delirium. The confusion assessment method for the ICU (CAM-ICU) is a validated delirium-screening tool for critically ill intubated patients. The aim of(More)
Association for Respiratory Care; and the American College of Critical Care Medicine. Chest 2001; 120:375S-395S 4. Boles JM, Bion J, Connors A, et al: Weaning from mechanical ventila­ tion. Eur RespirJ 2007; 29 :1033-1056 5. Penuelas O, Frutos-Vivar F, Fernandez C, et al; Ventila Group: Characteristics and outcomes of ventilated patients according to time(More)
PURPOSE OF REVIEW There is recognition that the use of sedative drugs in critically ill patients is potentially harmful, particularly in relation to ICU delirium and clinical outcomes. In that context, there is an increasing interest in maintaining light sedation, the use of non-gamma-aminobutyric acid agonist agents and antipsychotics. RECENT FINDINGS(More)
Os médicos intensivistas diariamente encaram pacientes que sofrem de delirium, desordem que causa considerável desconforto a pacientes e familiares, e que prevê desfechos piores para esses pacientes, inclusive demência e morte. Com a utilização rotineira de ferramentas de triagem, o delirium é, hoje, identificado em pacientes que antigamente eram(More)
Reade et al. studied 20 agitated intubated patients in a pilot open-label trial comparing the efficacy of dexmedetomidine versus haloperidol in facilitating extubation. While the study design had limitations, which are outlined by the authors themselves in the paper published in this issue of Critical Care, the study demonstrated an impressive reduction in(More)
The scientific evidence is irrefutable—delirium in the intensive care unit is an independent predictor of death and acquired dementia. 2 The linked study by Van den Boogaard and colleagues (doi:10.1136/bmj.e420) is the largest study on delirium in intensive care to date, and it provides a risk model to determine the likelihood of patients in intensive care(More)