Valerie Flook

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Reduction in ascent speed and an increase in the O2 tension in the inspired air have been used to reduce the risk for decompression sickness. It has previously been reported that decompression speed and O2 partial pressure are linearly related for human decompressions from saturation hyperbaric exposures. The constant of proportionality K (K = rate/partial(More)
An initial occupational survey (OS) was initiated to investigate the prevalence of venous gas embolism (VGE) in chamber attendants assisting hyperbaric oxygen (HBO2) treatments. Nine female subjects were exposed for three consecutive days to the routine hospital procedure of compressed air exposure to 240 kPa for approximately 115 min with 12 min of(More)
Partition coefficients were determined for blood, brain, heart, kidney, liver and skeletal muscle. The mean blood/gas coefficient was 0.461 for nitrous oxide and 0.68 for cyclopropane. The mean tissue/blood coefficients which differed significantly from unity were, for nitrous oxide, heart 0.83, kidney 0.83, liver 0.91, muscle 0.76 and, for cyclopropane,(More)
  • Valerie Flook
  • Undersea & hyperbaric medicine : journal of the…
  • 2011
This paper describes an attempt to calibrate a mathematical model that predicts the extent of bubble formation in both the tissue and blood of subjects experiencing decompression from a hyperbaric exposure. The model combines an inert gas dynamics model for uptake and elimination of inert anesthetic gases with a simple model of bubble dynamics in perfused(More)
The construction of an artificial circulation for the study of thrombolysis allowing variation in fluid pressure and flow rate is described. The lysis of 125I-fibrin was not influenced by variation in pressure between 10 and 30 cm H2O, but was significantly faster at a flow rate of 25 ml/min than at 40 ml/min or 10 ml/min. At equivalent concentrations as(More)