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Impairment of Coronary Arteriolar Endothelium-Dependent Dilation after Multi-Walled Carbon Nanotube Inhalation: A Time-Course Study
Engineered nanomaterials have been developed for widespread applications due to many highly unique and desirable characteristics. The purpose of this study was to assess pulmonary inflammation andExpand
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Maternal engineered nanomaterial exposure and fetal microvascular function: does the Barker hypothesis apply?
OBJECTIVE The continued development and use of engineered nanomaterials (ENM) has given rise to concerns over the potential for human health effects. Although the understanding of cardiovascular ENMExpand
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Microvascular and mitochondrial dysfunction in the female F1 generation after gestational TiO2 nanoparticle exposure
Abstract Due to the ongoing evolution of nanotechnology, there is a growing need to assess the toxicological outcomes in under-studied populations in order to properly consider the potential ofExpand
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Temporal Changes in Rat Liver Gene Expression after Acute Cadmium and Chromium Exposure
U.S. Service Members and civilians are at risk of exposure to a variety of environmental health hazards throughout their normal duty activities and in industrial occupations. Metals are widely usedExpand
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Whole-body nanoparticle aerosol inhalation exposures.
Inhalation is the most likely exposure route for individuals working with aerosolizable engineered nano-materials (ENM). To properly perform nanoparticle inhalation toxicology studies, the aerosolsExpand
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Pulmonary Cerium Dioxide Nanoparticle Exposure Differentially Impairs Coronary and Mesenteric Arteriolar Reactivity
Cerium dioxide nanoparticles (CeO2 NPs) are an engineered nanomaterial (ENM) that possesses unique catalytic, oxidative, and reductive properties. Currently, CeO2 NPs are being used as a fuelExpand
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Cardiac and mitochondrial dysfunction following acute pulmonary exposure to mountaintop removal mining particulate matter.
Throughout the United States, air pollution correlates with adverse health outcomes, and cardiovascular disease incidence is commonly increased following environmental exposure. In areas surroundingExpand
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Intravenous and gastric cerium dioxide nanoparticle exposure disrupts microvascular smooth muscle signaling.
Cerium dioxide nanoparticles (CeO2 NP) hold great therapeutic potential, but the in vivo effects of non-pulmonary exposure routes are unclear. The first aim was to determine whether microvascularExpand
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Xenobiotic Particle Exposure and Microvascular Endpoints: A Call to Arms
Please cite this paper as: Stapleton PA, Minarchick VC, McCawley M, Knuckles TL and Nurkiewicz TR. Xenobiotic Particle Exposure and Microvascular Endpoints: A Call to Arms. Microcirculation 19:Expand
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Cerium Dioxide Nanoparticle Exposure Improves Microvascular Dysfunction and Reduces Oxidative Stress in Spontaneously Hypertensive Rats
The elevated production of reactive oxygen species (ROS) in the vascular wall is associated with cardiovascular diseases such as hypertension. This increase in oxidative stress contributes to variousExpand
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