Valeria V. Isaeva

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This paper presents a topological interpretation of some developmental events through the use of well-known concepts and theorems of combinatorial geometry. The organization of early embryo using a simulation of cleavage considering only blastomere contacts is examined. Each blastomere is modeled as a topological cell and whole embryo--as cell packing. The(More)
The review presents a topological interpretation of some morphogenetic events through the use of well-known mathematical concepts and theorems. Spatial organization of the biological fields is analyzable in topological terms. Topological singularities inevitably emerging in biological morphogenesis are retained and transformed during pattern formation. It(More)
It has been noted that the integration of modern data of paleontology, comparative morphology, developmental biology, and molecular genetics forms the basis for understanding the mechanisms of evolutionary transformations of ontogeny. Paleontological and morphological evidence of the evolutionary changes in ontogeny are considered based on the data of cell(More)
The organism physiological systems forming a hierarchic network with mutual dependence and subordination can be considered as systems with non-linear dynamics including positive and negative feedbacks. In the course of evolution there occurred selection of robust, flexible, modular systems capable for adaptive self-organization by non-linear interaction of(More)
The classical embryological conception of egg cortex localization of morphogenetic determinants is interpreted in terms of current data on cell cortex and cell surface organization. The egg surface complex that involves cortical cytoskeleton--oolemma (stabilized with transmembrane linkage between the cytoskeleton and ligands of egg envelope extracellular(More)
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