Valeria Epshteyn

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We examined how cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates heterogeneous CD4(+) T cell responses by using experimental autoimmune encephalomyelitis (EAE), a CD4(+) T cell-mediated disease that is subject to regulation by CTLA-4. Disease incidence and severity were used as measures of in vivo CD4(+) T cell responses. The frequency, cytokine(More)
The ATLAS Forward Calorimeter (FCal) is a unique calorimeter featuring cylindrical electrodes with thin tubular liquid argon gaps. The design is well adapted to meet the physics requirements for the forward region in the ATLAS experiment at the Large Hadron Collider (LHC) at CERN, Geneva, Switzerland. A pre-production module of the electromagnetic section(More)
Acute myeloid leukemia (AML) continues to be a challenging disease to treat, thus new treatment strategies are needed. In this study, we investigated the antileukemic effects of ATR inhibition alone or combined with cytarabine in AML cells. Treatment with the ATR-selective inhibitor AZ20 caused proliferation inhibition in AML cell lines and primary patient(More)
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