Valentina Prone

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A Caucasian 36-year-old woman was affected by RRMS of 17 years duration. Interferon beta treatment was interrupted on April 2012 for lack of efficacy (3 relapses over the last 2 years). The patient had neutropenia (1.5 9 10/L) during this therapy, requiring transient dosage reduction. AntiJCV antibodies were positive and FTY was begun, according to the(More)
Susac syndrome (SS) is a rare syndrome defined by the clinical triad of encephalopathy, branch retinal artery occlusions (BRAOs) and hearing loss [1]. It is probably caused by obstruction of pre-capillary arterioles of the brain, retina and inner ear due to damage from anti-endothelial cell antibodies [2]. It affects women and men in the ratio of 3:1,(More)
The headache may be considered among the neuropathic pain syndromes of multiple sclerosis (MS). Several studies have showed that it is more frequent in MS patients than in controls or general population. Headache may occur at the pre-symptomatic phase, at clinical onset and during the course of the disease. Tension-type headache and migraine without aura(More)
Dear Sir, Originally described in 1900, progressive hemiplegia also known as Mills syndrome [1] is a rare, slowly progressive, motor neuron disease. However, many reports [1–4] date back to times when diagnostic methods did not allow reliable differential diagnosis, so the existence of this entity is debated [5, 6]. A more recent report suggested that(More)
Hemiplegic migraine (HM) is a rare migraine with aura; it can be familiar or sporadic. A 46-years-old man presented left migraine followed by right hemiparesis with bilateral plantar flexion of cutaneous plantar reflex (CPR). Brain CT and CT-angiography were normal. The next day patient got worse. The EEG showed left fronto-temporal cuspidate delta waves(More)
We describe the case of a 18-year-old woman affected by relapsing-remitting multiple sclerosis (RR MS) presented prolonged unusual orthostatic headache after lumbar puncture (LP), with Quincke needle (size of 20 gauge), done for MS diagnosis. Two months later orthostatic headache was still severe. Brain MRI showed a diffuse pachymeningeal enhancement (DPE)(More)
The appropriate treatment approach for elderly patients with glioblastoma multiforme (GBM) is unclear, although different studies suggest survival benefit in fit patients treated with radiotherapy and chemiotherapy after surgery. We performed a retrospective analysis of 151 patients older than 65years with GBM treated in 3 Lombardia Hospitals. In univariate(More)
INTRODUCTION A persistent primitive trigeminal artery (PTA) is the most common type of fetal carotid-basilar anastomosis in adulthood; however, its prevalence is low and estimated between 0.1% and 0.7% in angiographic studies. PTA is usually diagnosed incidentally during an angiographic examination, though some symptomatic cases associated with cranial(More)
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