Valentina N Elokhina

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Novel 2-acetylamino-4-acetyl-5-aryl(heteryl)-1,3,4-thiadiazolines, 2-acetylamino-5-aryl(heteryl)-1,3,4-thiadiazoles, and some of their salts were prepared and studied by multinuclear 1H, 13C, 15N, 19F and 2D NMR spectroscopy. The acetylation of thiosemicarbazones is accompanied by ring closure to form the corresponding 1,3,4-thiadiazolines and(More)
Studies dealing with the design of new antituberculous agents based on goal-oriented synthesis have provided the agent Perchlosone which is similar to isoniazid and rifampicin, produces in tuberculostatic activity against sensitive laboratory cultured mycobacteria, produces an inhibitory action on polyresistant clinical strains. Experiments on animals(More)
5. G. Azadian-Boulanger and D. Bertin, Chim. Ther., 8, 451-454 (1973). 6. G. Baldratti, W. Barbieri, A. Consonni, et al., Experientia, 25, 1018-1021 (1969). 7. D. H. R. Barton, M. Day, R. H. Hesse, et al., J. Chem. Soc. Perkin Trans. I., 2252-2i56 (1975). 8. A. Bowers, T. G. Halsall, E. R. H. Jones, et al., J. Chem. Sot., 2555-2562 (1953). 9. J. A.(More)
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