Valentina Magni

Learn More
Common sequence variants have recently joined rare structural polymorphisms as genetic factors with strong evidence for association with schizophrenia. Here we extend our previous genome-wide association study and meta-analysis (totalling 7 946 cases and 19 036 controls) by examining an expanded set of variants using an enlarged follow-up sample (up to 10(More)
Epidemiological and genetic data support the notion that schizophrenia and bipolar disorder share genetic risk factors. In our previous genome-wide association study, meta-analysis and follow-up (totaling as many as 18 206 cases and 42 536 controls), we identified four loci showing genome-wide significant association with schizophrenia. Here we consider a(More)
Schizophrenia is a complex disorder mainly characterized by thought disturbances, hallucinations, and decay of social and cognitive performances. From past attempts to identify the exclusive brain lesions responsible for specific domains of schizophrenia symptoms such as delusion and auditory hallucinations, recent data pointed towards network alterations(More)
OBJECTIVES To investigate the inter-hemispheric connections between the dorsal premotor cortex (dPM) and contralateral primary motor cortex (M1) in schizophrenia. METHODS Sixteen medicated, nine unmedicated schizophrenia patients and 20 healthy age-matched subjects were studied by twin-coil Transcranial Magnetic Stimulation. To activate distinct(More)
Several contributions have reported an altered expression of pseudoneglect in psychiatric disorders, highlighting the existence of an anomalous brain lateralization in affected subjects. Surprisingly, no studies have yet investigated pseudoneglect in first-degree relatives (FdR) of psychiatric patients. We investigated performance on "paper and pencil" line(More)
The Report on Confidential Enquiries into Maternal Deaths in England and Wales 1982-84 (Department of Health 1989) recommends early involvement of the anaesthetist in women having emergency caesarean sections and the use of epidural anaesthesia in preference to general anaesthesia. In an observational prospective study the need for emergency abdominal(More)
Design procedures and fabrication techniques of variable reflectance dielectric mirrors for laser output couplers are proposed. The design criteria, based on the use of only one shaped layer in a multilayer structure, yield any peak value and shape of the reflectance profile. The deposition technique of the variable thickness layer consists of a sputtering(More)
Resonators for Kerr-lens mode-locked lasers are studied with the help of an analytical model, and a new design procedure is presented. The experiments performed with a femtosecond Ti:sapphire laser demonstrate that this model permits an effective resonator design and offers reliable guidelines for the final experimental optimization. With a suitable(More)
Two novel stability diagrams are proposed, which provide a clear understanding of the behavior of solid-state laser resonators with focusing rods. By means of this graphic analysis, information on the stability boundaries, dynamic stability, misalignment sensitivity, and spot size in the rod can be obtained. On the basis of these diagrams the complicated(More)