Learn More
A randomized controlled study included 44 patients with acute myocardial infarction. It was found that intracoronary injection of bone marrow mononuclear cells is safe, ensures fixation of the injected cells in the myocardium, reduces blood levels of IL-1β and TNF-α, increases the content insulin-like growth factor, and does not provoke malignant(More)
We studied the cardioprotective effect of anti-ischemic drug trimetazidine in the thrombolytic therapy of acute myocardial infarction. Trimetazidine (60 mg/day) effectively inhibits lipid peroxidation and moderates reperfusion damage to the myocardium assessed by ECG, QRS index of damaged heart, and release of creatine phosphokinase into circulation.
AIM To evaluate effects of histochrome on severity of reperfusion damage in opening of the coronary artery in patients with acute myocardial infarction (MI). MATERIAL AND METHODS 86 acute MI patients were randomized into three groups. 26 patients of group 1 A received 100 mg histochrome 10 min before and 1 hour after intravenous bolus administration of(More)
Antitachycardia pacing and low energy cardioversion terminated episodes of ventricular tachycardia and fibrillation and prevented extrasystoles in patients with acute myocardial infarction, coronary artery disease, and long QT syndrome. Low energy automatic defibrillation was used in 25 patients intraoperatively and during the early postoperative period.(More)
BACKGROUND Complete following existing guidelines for management of acute coronary syndrome (ACS) is known to be associated with better outcomes. Partly this is explained by lesser adherence to recommendations in high risk patients. Aim of our study was to assess relationship between degree of following current guidelines and in hospital outcomes(More)
The effect of intracoronary streptokinase administration (31 patients), verapamil treatment (23 patients) and conventional therapy (27 patients) on the size of the affected area was examined in patients with acute myocardial infarction (MI). Streptokinase was administered in a dose of 250,000-500,000 IU within the first 3 to 20 hours of myocardial(More)
We studied the antithrombotic and thrombolytic effects of Trombovazim, a highlypurified proteolytic enzyme preparation obtained by immobilization of bacterial proteinases (Bacillus) on polyethylene oxide with a molecular weight of 1.5 kDa. Blood absorption of the preparation was evaluated after intragastric administration. In vitro experiments showed that(More)
The efficacy and risk of prehospital thrombolysis for acute myocardial infarction (MI) were evaluated in a randomized trial. Patients received streptokinase, 500,000 U, and heparin, 10,000 U, intravenously within 5-10 minutes before (Group 1, n = 50) or after (Group 2, n = 50) hospital admission. One hundred patients took conventional therapy (Group 3). The(More)