Vaithianathan Venkatasubramanian

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H azard and operability analysis (HAZOP) is widely used in process hazard analysis of chemical processes. But it is time and effort consuming. To aid human experts in conducting HAZOP analysis in a more thorough and systematic way, a software system (PHASuite) for automated HAZOP analysis has been developed. PHASuite can greatly increase the efficiency of(More)
Quantitative modelling and analysis of biochemical networks is challenging because of the inherent complexities and nonlinearities of the system and the limited availability of parameter values. Even if a mathematical model of the network can be developed, the lack of large-scale good-quality data makes accurate estimation of a large number of parameters(More)
Biochemical systems embed complex networks and hence development and analysis of their detailed models pose a challenge for computation. Coarse-grained biochemical models, called reduced-order models (ROMs), consisting of essential biochemical mechanisms are more useful for computational analysis and for studying important features of a biochemical network.(More)