Vaidya Jayathirtha Rao

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  • V. Rao, S. Rao
  • 2012
Cloud is gaining popularity as means for saving cost of IT ownership and accelerating time to market due to ready-to-use, dynamically scalable computing infrastructure and software services offered on Cloud on pay-per-use basis. There is a an important change in the way these infrastructures are assembled, configured and managed. In this research we(More)
New s-triazine derivatives 13a–h were synthesized for the structure–activity relationship studies as potent anticancer agents. The prepared analogues were evaluated for their in vitro inhibitory activity against the growth of PA-1 (Ovarian cancer), A549 (Lung cancer), MCF-7 (Breast cancer), and HT-29 (Colon cancer). Tri-substituted s-triazine derivatives(More)
A facile route for the synthesis of 20 new 1,4-disubstituted tetrazolone derivatives from allyl bromides of Baylis–Hillman adducts and various 1-substituted tetrazolones is described. All the synthesized compounds were screened for in vitro antibacterial and antifungal activity. Out of 20 newly synthesized compounds 16 compounds showed very good activity(More)
A series of new nicotinyl-rhodanine derivatives were synthesized by condensing various chloronicotinaldehydes with rhodanine and substituted rhodanines. The in vitro antitumor activity for these compounds was screened against MCF-7, A549 and HT29 human cancer cell lines. The results show that compounds 1, 3, 5, 7, 8 and 9 are more potent against MCF-7 cell(More)
Two new series of s-triazine derivatives appended with benzimidazole (15a–h) and benzothiazole derivatives (16a–h) are synthesized, and structure–activity relationships on anticancer activity of these 15a–h and 16a–h were probed. In vitro inhibitory activity against the growth of six cancer cell lines, viz., MCF-7, MDAMB-231, PC-3, DU-145, HT-29 and HGC-27(More)
A naphthalimide based fluorescent probe '1' that operates based on photoinduced electron transfer phenomenon is synthesized and its chemosensory application is explored. Among various metal ions, 1 selectively detects Fe(3+) with a detection limit of 3.0 × 10(-8) M. 1 is stable at physiological pH, nontoxic under experimental conditions and suitable for the(More)
This study presents the synthesis of 14 new 1,4-disubstituted piperazine derivatives from allyl bromides of Baylis–Hillman adduct and 4,4-disubstituted benzhydryl piperazines. All the synthesized compounds were further screened for in vitro ACE inhibitor and antimicrobial activities. Among the synthesized piperazine derivatives, compound 12h showed moderate(More)
Baylis–Hillman adduct-derived N-cinnamyl-substituted isatin derivatives were synthesized and evaluated for their antitubercular activity on Mycobacterium tuberculosis H37Rv strain ATCC 27294 by agar dilution method. Anticancer activity for the same compounds was also screened on four different cell lines: Chinese hamster ovary (CHO cells), Colo 205 (human(More)
Integrated Circuit(IC) design has seen a revolutionary progress in the past two decades with shrinking sizes of VLSI fabrication processes. This has an advantage of fabricating millions of transistors in a single chip IC. On the other hand it also creates many challenges in Deep Sub-Micron (DSM) technologies. One of the greatest challenges in DSM designs is(More)
Photochemical dehydrogenation of various substituted 3,4-dihydro-2-pyridones was achieved in a very efficient way by employing 10-15 mol% of photo-induced electron transfer sensitizers like 9-cyanoanthracene, 9-cyanophenanthrene and 1-cyanonaphthalene in presence of molecular oxygen, for the first time.
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